Erectile dysfunction (ED) happens when a man has ongoing problems getting and keeping an erection. Without treatment, ED can make sex difficult. The problem is reported by 1 in 5 men, and that number gets bigger with age.
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Erectile dysfunction can be treated at any age. Treatment depends on your overall health and the underlying cause of the problem.
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Men with diabetes, radical prostatectomy, and other complicating factors may still benefit from treatment with a phosphodiesterase type-5 inhibitor such as Viagra. Patients who fail a trial of PDE5 inhibitor should be informed of the benefits and risks of other therapies. This of a different PDE5 inhibitor is unlikely to have a profound effect on sexual function and someone who fails a first drug trial, but should be considered in selected cases. Second-line therapies include intra-urethral suppositories, intra-cavernous drug injection, vacuum-constriction devices, and penile prosthesis. Medicated Urethral System for Erection (MUSE). MUSE is an intra-urethral suppository of alprostadil, of vaso-active drug that relaxes smooth muscle in the penis and induces penile erection. Although not as effective as intra-cavernosal penile injection, MUSE is a less invasive treatment option. An initial trial dose of intra-urethral alprostadil should be administered under healthcare provider supervision due to the risk of fainting. The cost of intra-urethral suppositories is high with respect to the overall success and therefore should be used judiciously.
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Objective To conduct a systematic review and meta-analysis evaluating the effects of physical activity modalities and exercise on erectile function in erectile dysfunction trials.
35-90% of diabetic men also experience ED. Hyperglycemia can have a negative impact on several aspects of erectile function. Complications and changes associated with diabetes can compromise macrovascular and microvascular structures, the nervous system, and blood vessel linings.
A healthy nervous system that conducts nerve impulses in the brain, spinal column, and penisHealthy arteries in and near the corpora cavernosa that when stimulated can bring increased blood flow into the penisHealthy muscles and fibrous tissues within the corpora cavernosa, which can distend to allow the penis to fill with bloodAdequate levels of nitric oxide in the penisNormal-functioning tunica albuginea that allows for compression of the veinsAppropriate psychosocial interactions
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Due to the fact that ED and CVD share many of the same risk factors, it is not surprising that there is a high incidence of ED in men who present with CVD. A study by Montorsi et al found that ED was present in roughly 50% of patients with acute chest pain and confirmed CAD on angiography.21
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repaglinide (Prandin)nateglinide (Starlix)Canagliflozin (Invokana) and dapagliflozin (Farxiga)
Erectile dysfunction has various physical and psychological causes. It is often associated with conditions that affect blood flow in the penis, including diabetes, high cholesterol, high blood pressure, cigarette smoking, obesity and heart disease. Other factors commonly linked to erectile dysfunction include older age, low testosterone levels, alcohol or drug use, anxiety and depression.
Erectile Dysfunction (ED), also known as impotence, is a type of male sexual dysfunction characterized by the inability to maintain an erection long enough and firm enough for sexual intercourse.